A creeping, succulent mat-forming
perennial herb, with rounded stems rooting at the nodes. Leaves are
opposite, ovate, dentate, shallowly 3-cleft, glossy and green. Flowers
are 2 cm across and golden yellow.
Makes an excellent and decorative ground cover.
• Study isolated main bioactive
sesquiterpene lactones, trilobolid-6-O-isobutyrates A and B.
• From the flower, the structure of trilobolide-6-O-isobytyrate
shows a eudesmanolide sesquiterpene skeleton.
• Contains the diterpene (kaurenoic acid), eudesmanolide lactones and luteolin (in leaves and stems.
• Study isolated
• No reported folkloric medicinal use in the Philippines.
• In Trinidad and
Tobago, used for reproductive
problems, amenorrhea, dysmenorrhea.
• In South
used to treat symptoms of colds and flu; for fevers and inflammations.
An investigation of four herbal drugs, including Sphagneticola trilobata,
on the anti-inflammatory activity of Central American plants used in
traditional medicine, showed all the extracts reduced croton oil-induced
ear dermatitis. Results suggest the lipophilic extracts to be potential
sources of antiinflammatory activity.
A study of the n-hexane extract of Wedelia trilobata showed antibacterial
activity against Bacilus subtilis, Mycobacterium smegmatis, Pseudomonas
aeruginosa, Salmonella group C, S paratyphi and Shigella sonnei.
Study in mice on the analgesic activity of the ethanol extracts of W trilobata, W bilofra and E alba showed dose-dependent blocking of writhing response.