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Family Dioscoreaceae
Dioscorea bulbifera Linn.

Huang du

Scientific names Common names
Dioscorea bulbifera Linn. Aribukbuk (Ilk.)
Dioscorea heterophylla Roxb. Bayag-kabayo (Tag.)
Dioscorea latifolia Benth. Dadakan (Bag.)
Dioscorea oppositifolia Campbell Pulugan (Bik.)
Dioscorea sativa Hort. Ubi-ubihan (Tag.)
Dioscorea violacea Baudon Utong-utoñgan (Tag.)
Dioscorrea tamifolia Salisb. Aerial yam (Engl.)
Helmia bulbifera (L.) Kunth. Air potato (Engl.)
Huang du (Chin.) Bitter yam (Engl.)
  Potato yam (Engl.)
  Huang yao zu (Chin.)

Other vernacular names
BENGALI: Ban Alu, Rat Alu, Roth Alu.
BURMESE: Ah Lu Thi, Hpwut Sa Uu, Pat Sa Uu.
CHINESE: Shan ci gu, Ling yu shu, Huang yao, Shan ci gu.
FRENCH: Igname Bulbifère, Igname Pousse En L´air, Masako, Pomme En L´air, Pousse En L´air.
GERMAN: Brotwurzel, Kartoffelyam, Knollen-yam, Luft-Kartoffel, Luft-yams, Yamswurzel
HINDI: Gaithi, Hoei Oepas, Karu Kunda, Karukanda, Kodikilangu, Ratalu, Ratula
INIDIA: Hoei-Oepas
JAPANESE: Kashuu Imo, Niga Kashuu.
MARATHI: Kadu Kand, Mataru.
NEPALESE: Giitthaa (Gittha), Giitthe Tarul (Gitthe Tarul), Jada Bis, Van Tarul.
ORIYA: PitaaAlu.
RUSSIAN: Iams Lukovitsenosnyi.
SPANISH: ñame Criollo, ñame De Aire,, ñame De Gunda, ñame Volador, Papa Cimarrona, Papa De Aire.
TELUGU: Adavi Dumpa, Chedupaddudampa, Karu Kanda, Malaka Kayependalamu.
THAI: De Khwa, Ham Pao, La Sa Mi, Lo Chae Mue, Man Khamin, Wan Phra Chim, Wan Sam Phan Thueng
VIETNAMESE: C di, Khoai dái, Khoai tri.

Ubi-ubihan is a climbing or twining, dioecious, smooth, unarmed vine reaching a length of several meters. Tubers are rounded, not larger than a man's fist. Stems are terete, bearing numerous little tubers. Leaves are simple, ovate, 7 to 14 centimeters long, with a broad and prominently heart-shaped base, broad and rounded sinus, rounded lobes, and 7- to 9-nerved. Spikes are slender, panicled, numerous, 8 to 10 centimeters long, and rather densely many-flowered. Flowers are about 3 millimeters long. Capsules are longer than broad. Seeds are winged at the base only.

- In thickets at low and medium altitudes.
- Sometimes cultivated as an oddity for its tubers.
- Also occurs in India to China and Malaya.

- Tubers reported to contain a poisonous glucoside.
- Tuber extract is rich in flavonoid, phenolics, reducing sugars, starch, diosgenin, ascorbic acid, and citric acid.
- Study yielded14 compounds: : stigmasterol, mono-arachidin, 1,7-bis-(4-hydroxyphenyl)-1E,4E,6E-heptatrien-3-one, behenic acid, demethyl batatasin IV, 2,3'-di-hydroxy-4',5'-dimethoxybibenzyl, diosbulbin B, diosbulbin D, docosyl ferulate, 7-bis-(4-hydroxyphenyl) -4E, 6E-heptadien-3-one, 5,3,4-trihydroxy-3,7-dimethoxyflavone, tristin, protocatechuic acid, adenosine.
- Study yielded three norclerodane diterpenoids: diosbulbins K-M, and one enoglycoside, diosbulbinoside G, with four norclerodane diterpenoids, disobulbins B, E, F and G from the rhizomes.

- In the wild, tubers, when fresh, are bitter.
- Cultivated tubers are less or non-bitter.
- Tubers considered tonic, expectorant, aphrodisiac and anthelmintic.

Parts used


Edibility / Culinary
- Tubers are reported edible, with a flavor similar to potato.
- Some report the tubers are poisonous when raw.
- Tubers taken internally as remedy for dysentery and syphilis.
- Tubers used as resolvent for boils and as diuretic.
- Powdered tubers used as application for sores, piles and to stop diarrhea.
- In India, a folk remedy used to cure wounds, leucoderma and boils. Also, used as tonic, expectorant in asthma, as aphrodisiac and anthelmintic.
- In Chinese medicine, used to treat diseases of the lungs, kidney, spleen and many types of diarrhea.

Anticancer screen carried out in vivo with HepA in mice showed active anticancer compounds from the hydrophobic constituents of D. bulbifera. The anticancer effects were related to direct toxicity on tumor cells.
Liver Toxicity Studies: Study to evaluate the liver-toxic fraction in Rhigoma of Dioscorea bulbifera is rats showed significant liver toxicity. The chloroform extract was the liver toxic fraction.
Antioxidant: Study showed impressive levels of enzymatic (GPx, CAT, SOD, G6PD, GST) and commendable stores of non-enzymatic antioxidants (reduced GSH, vitamins C and E).
Antitumor Promoting / Constituents: Study of rhizome extracts yielded 28 compounds. some showed different inhibitory activities against tumor promotion of JB6 (CI22 and CI41) cells. The EtOAc and n-BuOH fractions were found to be potent anti-tumor promoters.
Hepatotoxicity: Study in mice showed the EtOAc fraction contains the main toxic ingredients of D. bulbifera rhizome, and the mechanism of hepatotoxicity may be due to liver oxidative stress injury in mice.
Wound Healing: Study of tuber extract revealed significant wound healing activity, high rate of wound contraction and decrease in the period for epithelization.
Antihyperglycemic / Antidyslipidemic: Study of aqueous extract of tubers in glucose-primed and STZ-treated Wistar rats showed significant antihyperglycemic and antidyslipidemic effects.
Myocardial Protective Effect: Study of hydroalcoholic extract showed D. bulbifera could ameliorate myocardial ischemia and reperfusion injury by improving ventricular function and inhibition of cardiomyocyte necrosis and apoptosis.
Anthelmintic: Study of D. bulbifera extract showed significant anthelmintic activity, especially against Eicinia fetida, Ascardia galli and Raillietina spiralis. Results provide a rationale for its traditional use as an anthelmintic.
Analgesic / Anti-Inflammatory: Study of aqueous and methanol extracts from the dry bulbils of D. bulbifera L. var sativa showed a dose-dependent inhibition of pain and inflammation. The exhibited potent analgesic and anti-inflammatory effects may result from inhibition of inflammatory mediators such as histamine, serotonin and prostaglandins.
Hepatotoxicity: Study investigated the hepatotoxicity induced by D. bulbifera in mice. Results showed the EtOAc fraction (EF) contains the main toxic ingredients of D. bulbifera rhizome, and the mechanism of hepatotoxicity induced by it may be due to liver oxidative stress injury in mice.
Antidiabetic Activity: A preliminary study has shown antihyperglycemic and antihyperlipidemic activity of D. bulbifera on Wistar rats. Study explored D. bulbifera as potential glycosidase inhibitors. D bulbifera showed significant inhibition with porcine pancreatic amylase and crude murine glucosidase as well as pure a-glucosidase. It suggests a potential as an effective herbal formulation in combinational therapy.
Nanoparticles using D. bulbifera / Synergism with Antimicrobial Agents: Study is the first report on the synthesis of silver nanoparticles using D. bulbifera tuber extract, with an estimation of its synergistic potential for enhancement of the antibacterial activity of broad spectrum antimicrobial agents.


Last Update April 2013

IMAGE SOURCE :Dioscorea bulbifera / Forest and Kim Starr / Plants of Hawaii / click on image to go to source page / Creative Commons Attribution 3.0 License / alterVISTA
OTHER IMAGE SOURCE: Leaf Closeup / Dioscorea bulbifera / Leaves at Tree Top Park, Florida / Forest and Kim Starr - Plants of Hawaii / Creative Commons Attribution / alterVISTA
OTHER IMAGE SOURCE: Bulb / click on image to go to source page / Dioscorea bulbifera / ThailandPLANT

Additional Sources and Suggested Readings
Sorting Dioscorea names / Multilingual Multiscript Plant Name Database
Anticancer effects of various fractions extracted from Dioscorea bulbifera on mice bearing HepA / Zhongguo Zhong Yao Za Zhi, 2004 Jun;29(6):563-7.
Studies on liver-toxicity in rhigoma of Dioscorea bulbifera
/ Xing-Qi Tan, Jin-Lan Ruan et al / Zhongguo Zhong yao za zhi Zhongguo zhongyao zazhi China journal of Chinese materia medica (2003), Vol 28, Issue: 7, Pages: 661-663 / PubMed ID: 15139116/
Screening of antioxidant potentials in Dioscorea bulbifera / M Suriyavathana and S Indupriya / Int. J. of Pharm. & Life Sci. (IJPLS), Vol. 2, Issue 4: April: 2011, 661-664
Constituents from anti-tumor-promoting active part of Dioscorea bulbifera L. in JB6 mouse epidermal cells / Hyiyuan Gao, Bailling Hou et al / Asian Journal of Traditional Medicines, 2007, 2 ( 3 )
Study of the hepatotoxicity induced by Dioscorea bulbifera L. rhizome in mice. / Wang J, Ji L, Liu H, Wang Z / Biosci Trends. 2010 Apr;4(2):79-85.
Wound Healing Activity of Dioscorea bulbifera Linn / Panduraju.T,Veera Raghavulu Bitra et al / Journal of Pharmacy Research, Vol 3, No 12 (2010)
/ Zabeer Ahmed, Mohd Zahoor Chishti, Rakesh Kamal Johri et al / Diabetologia Croatica 38-3, 2009
Chemical constituents from tubers of Dioscorea bulbifera / Gang Wang, Binbin Lin, Jinsong Li et al / Zhongguo Zhong yao za zhi Zhongguo zhongyao zazhi China journal of Chinese materia medica (2009)
Vol 34, Issue: 13, Pages: 1679-1682 / PubMed ID: 19873780
Norclerodane diterpenoids from rhizomes of Dioscorea bulbifera / Hai Liu, Gui-Xin Chou et al / Phytochemistry, Vol 71, Issue 10, July 2010, Pages 1174-1180 / doi:10.1016/j.phytochem.2010.04.002
Protective role of air potato (Dioscorea bulbifera) of yam family in myocardial ischemic reperfusion injury / Hannah Rachel Vasanthi, Subhendu Mukherjee et al / Food Funct., 2010, 1, 278–283
Investigation of anthelmintic potential of some plants claimed by tribals of satpuda hills / Satish B. Kosalge, Ravindra A. Fursule / Int.J. PharmTech Res.2009,1(1)
Analgesic and Anti-Inflammatory Properties of Extracts from the Bulbils of Dioscorea bulbifera L. var sativa (Dioscoreaceae) in Mice and Rats / M Mbiantcha, A Kamanyi, R B Teponno et al / Evidence-Based Complementary and Alternative Medicine, Vol 2011 (2011) / doi:10.1155/2011/912935
Dioscorea bulbifera L. (accepted name) / Chinese names / Catalogue of Life, China
Dioscorea bulbifera (Aerial Yam) / Common names / Zipcodezoo
Study of the hepatotoxicity induced by Dioscorea bulbifera L. rhizome in mice. / Wang J, Ji L, Liu H, Wang Z. / Biosci Trends. 2010 Apr;4(2):79-85.
Antidiabetic Activity of Gnidia glauca and Dioscorea bulbifera: Potent Amylase and Glucosidase Inhibitors /
Sougata Ghosh, Mehul Ahire, Sumersing Patil, Amit Jabgunde, Meenakshi Bhat Dusane, Bimba N. Joshi, Karishma Pardesi, Sanjay Jachak, Dilip D. Dhavale, and Balu A. Chopade / Evidence-Based Complementary and Alternative Medicine, Volume 2012 (2012) / doi:10.1155/2012/929051
Synthesis of silver nanoparticles using Dioscorea bulbifera tuber extract and evaluation of its synergistic potential in combination with antimicrobial agents / Ghosh S, Patil S, Ahire M, Kitture R, Kale S, Pardesi K, Cameotra SS, Bellare J, Dhavale DD, Jabgunde A, Chopade BA / International Journal of Nanomedicine, February 2012 Volume 2012:7 Pages 483 - 496 / DOI: http://dx.doi.org/10.2147/IJN.S24793

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