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Family Zingiberaceae
Kamia
Hedychium coronarium J. Koenig
GINGER LILY

Jing hua

Scientific names Common names
Amomum filiforme Hunter ex. Ridl. Banai (Bis.)
Gandasulium coronarium (J. Koenig) Kuntze Donsuli (Buk.) 
Gandasulium lingulatum (Hassk) Kuntze Kamia (Tag., Bik., Sp., C. Bis.)
Hedychium chrysoleucum Hook. Katkatan (Bis.)
Hedychium coronarium J.Koenig Katotant (Bis.)
Hedychium gndasulium Buch.-Ham. ex Wall. Gandasuli (Moro)
Hedychium lingulatum Hassk Butterfly flower (Engl.)
Hedychium maximum Roscoe Butterfly ginger (Engl.)
Hedychium prophetae Buch.-Ham. ex Wall. Butterfly lily (Engl.)
  Garland flower (Engll.)
  Garland lily (Engl.)
  Ginger lily (Engl.)
  White butterfly (Engl.)
. White ginger lily (Engl.)
Hedychium coronarium J.Koenig is an accepted name. The Plant List

Other vernacular names
BENGALI: Dolon champa.
CHINESE: Jing hua.
CUBA: Flor de mariposa.
FIJI: Cevuga vula.
HAWAIIAN: Awapuhi ke'oke'o.
HINDI: Dolan champa.
INDONESIA: Gondasuli, Gandasoli, Mandasuli.
MALAYSIA: Gandasuli, Suli.
KANNADA: Suruli sugandhi.
MARATHI: Sonataka.
NEPALESE: Dudh kevara.
THAI: Hanghong, Mahaahong, Tha haan, Hun kaeo.
SAMOA: Teuila paepae.
VIETNAM: B[aj]ch di[eej]p, Na[ar]i ti[ee]n.

Botany
Kamia is an erect shrub with a stout rootstock, growing 0.5 to 1.5 meters high. Leaves are smooth or the lower surfaces moderately hairy, lanceolate to oblong-lanceolate, 10 to 50 centimeters long, 3 to 11 centimeters wide, with slender pointed tip. Ligule is prominent, 1 to 3 centimeters long. Ellipsoid spike is at the top of the stem, 5 to 12 centimeters long. Bracts are green, ovate to obovate, about 4 centimeters long, and each with 2 or 3 very fragrant flowers, with a fragrance that is more pronounced in the evening. Calyx is tubular, clefted on one side, and about 4 centimeters long; lobes are narrow, involute, and about 4 centimeters long. Lip is obcordate or obovate, 5 to 6 centimeters in diameter, white and pale yellow in the center. Staminodes are white, oblong-elliptic, obtuse, narrowed at the base, 4 to 5 centimeters long and 2 to 2.5 centimeters wide. Capsule is oblong, smooth, many seeded, with orange-yellow valves inside. Aril is red.

Distribution
- Cultivated for ornamental use.
- In some regions of the southern Philippines, naturalized.

- Prehistoric introduction in Mindanao; recent in Luzon.
- Native of India, now pantropic in distribution.
- in many parts of India, the plant is becoming rare because of complete uprooting, early harvesting, and increase market demand for rhizomes and Ark (juice) extracted from the flowers. (26)

Constituents
- GC-MS study of essential oil from fresh and dried rhizomes yielded 44 and 38 constituents, representing 93.91% and 95.41%, respectively. Major components of EO from fresh and dried rhizomes were 1,8-cineole (41.42%, 37.44%), ß-pinene (10.39%, 17.4%), and α-terpineol (8.8%, 6.7%). (see study below) (1)
- Dried rhizome contains: starch, 3 %; glucose, 4.58 %; albumen, 1.65 %; fats, 0.33%; resinous acid, 3.
6%; resinous acid, 3.66%; resin, 5.93 %; extractive matter, 0.91%; essential oil; gum, 13.75 %; organic acids, 5.5%; cellulose, 29.68%.
- The flower yields a fragrant essential oil; the rhizome, a volatile oil.
- Study on rhizomes yielded coronarin -D, coronarin -D ethyl ether, coronarin -E, and a new diterpene identified as (+)-14β-hydroxylabda-8(17),12-dieno-16,15-lactone, assigned the trivial name of isocoronarin-D.
- Several labdane-type diterpenes--coronarin A, B, C, D, E, and F have been isolated from the rhizome.
- Water extract of H. coronarium yielded
carbohydrates, proteins, flavonoids, phenolic compounds, tannins, steroids and terpenoids, saponin, cardiac glycosides, and oil. (see study below) (15)
- Study of leaf and rhizome essential oils yielded β-Pinene (33.9%), α-pinene (14.7%), 1,8-cineole (13.3%), r-elemene (11.0%) and carotol (9.1%) as main components in the leaf oil, including 82.0% terpenoid compounds; and 1,8-cineole (37.3%), β-pinene (23.0%), α-terpineol (10.4%) and α-pinene (9.9%), comprising 80.6% as major constituents of the rhizome oil. (see study below) (18)
- Rhizomes yielded carbohydrates, flavonoids, saponins, steroids, and alkaloids. (see study below)
(21)
- Study of flowers isolated a new labdane-type trinorditerpene, coronadiene (3), along with 8 known compounds. The principal constituents, were coronaririn C and 15-hydroxylabda-8(17).11.13-trien-16,15-olide, (see study below) (27)
- Methanolic extract of rhizome yielded three new labdane-type diterpenes, hedychilactones A, B, and C, along with six known diterpenes. (see study below) (29)
- Study of rhizomes isolated cytotoxic principles: four new labdane-type diterpenes, coronarin A, B, C, and D. along with one known labdane-diterpene, (E)-labda-8(17)- 12-diene-15, 16-dial. (34)
-
Study of essential oil hydrodistilled from rhizome parts of four Hedychium species varied from 0.05 to 0.47% (v/w). GC-FID and GC-MS studies identified a total of 44 components accounting for 86.18-99.94% of the EO. The EOs were grouped into four chemotypes: eucalyptol (1), linalool (2), coronarin-E (3) and ß-pinene (4). The leaf oil of H. coronarium was characterized by
α-pinene (20%), linalool (15.8%), 1,8-cineole (10.7%), α-terpineol (8.69%), while the root yielded α-pinene (23.6%), α-humulene (17.1%), and ß-caryophyllene (17.0%). (35)

Properties
- Decoction of the rhizome is anti-rheumatic, tonic and excitant.
- In Ayurveda, considered febrifuge, tonic, stimulant and antirheumatic. (26)
- Powdered rhizome and essential oil considered anti-infective; roots essential oil considered anthelmintic and carminative. (26)
- Studies have shown antimicrobial, anti-inflammatory, antioxidant, antinociceptive and cytotoxic properties.

Parts utilized
Rhizome, stems, seeds, leaves.

Uses
Culinary
Young buds and flowers are edible. Used as flavoring.
Roots used as famine food.
Folkloric
- Decoction of stems near the rhizome used as a gargle for tonsillitis; or the raw stem chewed for same purpose.
- In the Moluccas the base of the stem is chewed and the juice applied to swellings.
- In Brazil decoction of rhizome is antirheumatic, tonic and excitant.
- In India, sold in bottles of extract called Gulbakawali Ark; used as eye tonic and for to prevent eye cataracts. Certain tribal groups of Bihar use the rhizome of the plant as febrifuge.
- In Bangladesh plant rhizome used for diabetes.
- In Chinese medicine, used for headache, inflammatory pains, rheumatism.
- In the Moluccas used as antirheumatic, tonic, and excitant.
- In Hawaii juice of mature seeds use as treatment for hair and skin afflictions.
- In Thailand, boiled leaves are applied to relieve stiff and sore joints.
- In India, used used as febrifuge, eye tonic, anthelmintic, antirheumatic, tranquilizer in various Ayurvedic medicines. (26)
Others
- Fragrant bouquets: In the provinces, the fragrant flowers popular in the making of wreaths and bridal bouquets.
- Wreaths: Stems are 45% cellulose, used in making paper.

Studies
• Antifungal / Antimicrobial / Essential Oil:
The essential oil from fresh and dry rhizomes yielded 44 and 38 constituents and was shown to have antifungal and antibacterial effects. Antibacterial effects were higher in the fresh sample than the dried; both showed activity against Trichoderma sp. and C. albicans, B. subtilis and P aeruginosa. (1)
Analgesic / Anti-inflammatory:
Different extracts of HC exhibited significant analgesic and anti-inflammatory activities. The effects could be due to inhibition of prostaglandin synthesis, inhibition of histamine and/or serotonin. (2)
Antibacterial / Cytotoxicity:
Study of methanol and dichlormethane extracts exhibited antibacterial activity against Gram positive (S aureus, B subtilis, B megaterium, Sarcina lutea) and Gram negative (E coli, S sonnei, S shiga, P aeruginosa and S typhi) bacteria. Cytotoxicity was evaluated against brine shrimp nauplii. (4)
Antioxidant / Anti-inflammatory:
Five genus of Zingiberaceae plants from Taiwan, including Hedychium, were studied for their functional properties. Hedychium sp. were found to have antioxidant properties. Most Zingiberaceae plant extracts exhibited antimicrobial activity against all food microorganisms; Hedychium did not show activity against E. coli and Vibrio parahemolyticus.
Flower Essential Oil / Anti-inflammatory:
Study on the oil exhibited significant inhibition of paw edema but showed poor antioxidant activity with DPPH. There was no direct correlation between inflammatory and antioxidant activity of the essential oil. (5)
Phenolics / Antioxidant:
Study showed HC to have the highest phenolic content and ascorbic acid equivalent antioxidant capacity of leaves of 26 ginger species.
Anticancer / Cytotoxic Labdane Diterpenes:
Study of hexane extract isolated two new labdane diterpenes, 1 and 2, along with 10 other known metabolites. Isolates were studied for cytotoxic activity against lung cancer, human neuroblastoma, breast cancer and cervical cancer cell lines. (8)
Labdane-type Diterpenes / Anti-Inflammatory:
Study yielded three new labdane diterpenes 1-3, named coronarins G, H, and I, together with 7 known coronarin D. Compounds 1, 2, and 6 (hedyforrestin C) showed to be potent inhibitors of LPS-stimulated TNF-a, IL-6, and IL-12 p40 productions. (9)
Trypanocidal / Essential Oils:
Study of essential oil of leaves and rhizomes of H. coronarium. Caryophyllene was the major component in rhizomes, which showed a remarkable activity against T. brucei strains, with highly increased trypanocidal activity in synergism with caryophyllene oxide plus pentamidine. (13)
Antiurolithiatic / Roots:
Study evaluated the antiurolithiatic activity of roots of Hedychium coronarium on experimental kidney stones. Alcoholic root extracts showed the highest dissolution of calcium oxalate stones. (14)
Phenolic Contents:
Study evaluated the water extracts of three different species of genus Hedychium i.e., H. spicatum, H. coronarium and H rubrum. Results showed all three contained a good quantity of phenolic compounds. (see constituents above) (15)
Anti-Venom / Essential Oil:
Study evaluated the potential inhibitory effects of H. coronarium essential oil of leaves on the coagulant and fibrinogenolytic activities induced by venoms of Lachesia muta, Bothrops atrox and Bothrops moojeni. Results showed the oils interact with venom proteases and plasma constituents, with inhibition of clotting effect when the oils were previously incubated with venoms. Results showed the essential oil can be used as alternative to complement serum therapy. (16)
Mosquitocidal / Dengue Vector Aedes aegypti:
Study evaluated the larvicidal activity of 3 different solvent extracts of H. coronarium against dengue vector Aedes aegypti. Results showed the methanol extract of HC to be more effective than other extracts. (17)
Antimicrobial / Mosquitocidal / Antioxidant / Leaf and Rhizome:
Study evaluated the essential oil, methanolic and aqueous extracts of leaves and rhizomes of H. coronarium. Leaf and rhizome oil exhibited significant antimicrobial activity against all five fungal and four bacterial strains tested, attributed to its high terpenoid contents. Both oils showed mosquito larvicidal activity, with β-Pinene, α-pinene and 1,8-cineol as the principal larvicidal components of both oils. Polar extracts showed antioxidant activity. (see constituents above) (18)
Ink Source / Flowers:
Study evaluated if H. coronarium flower extract is a feasible marker ink. Results showed the camias flower extract is a feasible color-changing marker ink for papers. (19)
Hypoglycemic / Rhizome:
Study evaluated the hypoglycemic effect of ethanolic extract of H. coronarium rhizome in alloxan induced diabetes rat model. Results showed significant reduction in blood glucose, serum insulin, serum catalase and haemoglobin in alloxan induced diabetic rats. (21)
Cytotoxicity / Phytochemicals / Rhizome:
Study evaluated a methanolic extract of rhizomes for phytochemicals and cytotoxicity activity by brine shrimp lethality bioassay. Screening yielded carbohydrates, flavonoids, saponins, steroids, and alkaloids. It showed potent cytotoxic activity on brine shrimp lethality assay with an LC50 value of 0.39 µg/ml, compared to LC50 of reference drug vincristine sulfate at 0.52 µg/ml. (22)
Floral Scent / Headspace Volatile Compounds:
Study of headspace volatile compounds of flowers yielded monoterpene hydrocarbons (34.9%), oxygenated monoterpenes (34.4%) and sesquiterpenes hydrocarbons (13.2%). Major components and major contributors to the flower scent were (E)-ß-ocimene (28.7%), linalool (19.3%), and 1,8-cineole (14.5%). (23)
Thiamethoxam:
Study evaluated the presence of thiamethoxam from water, soil, and rhizomes and leaves of H. coronarium. Thiamethoxam® (4-[(2-chloror-5-thiazoly)methyl]tetrahydro-5-methyl-N-nitro-4H-1,3,5-oxadiozin-4-imine) belongs to a new class of insecticides known as neonicotinoids, which act as agonists of the post-synaptic nicotinic acetylcholine receptors. Study showed the presence of thiamethoxam in leaves, but not in rhizomes. (24)
Antinociceptive / Rhizomes:
Study in mice evaluated the antinociceptive activity of a methanolic extract of H. coronarium rhizomes. Results showed substantial rise in pain threshold with the tail immersion method and writhing inhibition in acetic-acid induced writhing test. Diclofenac was used as standard. (25)
Hepatoprotective / D-Galactosamine Toxicity / Flowers:
Study on 80% aqueous acetone extract pf Hedychium coronarium flowers showed hepatoprotective effect on D-galactosamine-induced cytotoxicity in primary cultured mouse hepatocytes. Study isolated a new labdane-type trinorditerpene, coronadiene (3), along with 8 known compounds. The principal constituents, coronaririn C and 15-hydroxylabda-8(17).11.13-trien-16,15-olide, displayed hepatoprotective properties, with effects stronger than hepatoprotective agent, silybin. (27)
Analgesic / Central Nervous System Depressant Activity / Rhizome:
Study investigated the analgesic and neuropharmacological activities of a methanolic extract of rhizomes of Hedychium coronarium. Extract at doses of 100, 200, and 400 mg/kbw produced increase in pain threshold in tail immersion methods in a dose dependent manner. At 400 mg/kg dose, there was maximum of 72.12% writhing inhibition (p<0.001) comparable to inhibition by standard drug diclofenac sodium. On neuropharmacological testing using hole-cross and open field test in mice, the extract showed dose-dependent suppression of motor activity. (28)
Inhibition of Increase Vascular Permeability and Nitric Oxide Production / Rhizome:
Study of methanolic extract of rhizome was found to inhibit the increase in vascular permeability induced by acetic acid in mice, and nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages and iNOS induction. (see constituents above ) (29)
Antihypertensive / Leaf Blade:
Study evaluated 32 medicinal plants popularly used for diuretic and/or antihypertensive properties in conscious unrestrained rats. All extracts were made in aqueous ethannol (50:50 by volume) and administered per os. Antihypertensive effects in SHR rats were observed after administration of Allium sativum bulb, lea europaea leaf and Hedychium coronarium leaf blade. (30)
Leishmanicidal:
In a study of 94 ethanolic plant extracts used medicinally by the Yanesha, an Amazonian Peruvian ethnic group for affections related to leishmaniasis and malaria, eight species, including Hedychium coronarium, showed invitro activity against Leishmania amazonensis amastigotes with IC50s < 10 µg/ml. (31)
Antidiabetic / α-Amylase and α-Glucosidase Inhibitory Activity / Rhizome:
Study evaluated the antidiabetic effect of rhizomes by α-amylase and α-glucosidase inhibition assay. Among six different extracts, the EA extract showed highest inhibition. Subfractions yielded major compounds of fatty acids such as suberic acid and terpenes such as triparanol, ginkgolide C, and swietenine. Results suggest the rhizome extract and its active constituent has potential as natural inhibitor of the two carbohydrate metabolizing enzymes. (32)
Diuretic Effect / Leaf Blade:
Study evaluated 32 medicinal plats popularly used for presumed diuretic property in conscious unrestrained rats, using aqueous ethanol (50:50, v/v) given orally. The most significant diuretic effect was observed with Hedychium coronarium sheath and leaf-blade extracts. (33)
Essential Oil ./ Antimicrobial / Antioxidant / Rhizome Parts Study:
Study of essential oil hydrodistilled from rhizome parts of H. coronarium yielded 44 components accounting for 86.18-99.94% of the EO. Major components are ß-pinene (11.07-42.74%), eucalyptol (11.48-40.59%), linalool (1.56-45.11%),coronarin-E (1.01-39.57%). α-pinene (3.80-16.60%), p-cymene (1.05-8.89%), y-terpinene (1.73-5.82%) and 10-epi-y- eudesmol (1.11-4.86%). The EO exhibited considerable levels of reducing power activity (IC50 0.39--1.66 mg/ml), DPPH (IC%) 0.57-2.19 mg/ml), ABTS *IC500.12-0.67 mg/ml) radical scavenging activities. The EO showed good antimicrobial activity against Candida albicans and Fusarium oxysporum. (see constituents above) (35)
Anticancer / / Antiproliferative and Apoptotic / HeLa Cervical Cancer Cells:
Study evaluted the cytotoxicity of ethanol extract of H. coronarium by MTT and clonogenic survival assay. The HCEE significantly inhibited the survival of HeLa cells without affecting the viability of normal human umbilical vein endothelial cells and induced apoptosis in HeLa cells in a dose-dependent manner. Results showed Hedychium coronarium exerts antiproliferative and apoptotic effects against HeLa cells and has potential for use against cervical cancer. (36)
Cytotoxic Labdane Diterpenes/ / Anticancer / Rhizomes:
Study of hexane extract of rhizomes isolated two new labdane diterpenes along with 10 known metabolites. The cytotoxic isolates were studied against the A-549 (lung cancer), SK-N-SH (human neuroblastoma), MCF-7 (breast cancer), and HeLa (cervical cancer) cell lines. (37)
Labdane Diterpenes / Cancer Chemoprevention / Rhizomes:
Study of rhizomes isolated three labdane diterpenes, isocoronarin D (1), methoxycoronarin D (2), ethoxycoronarin D (3) and benzoyl eugenol (4). Chemopreventive potential was evaluated using in vitro assays i.e. inhibition of NF-kB, COX-1 and -2, and induction of antioxidant response element (ARE) and inhibition of cell proliferation. Results support the chemopreventive potential of H coronarium rhizome constituents (38)
Glucose Lowering Effect / Leaves:
Study evaluated the effect of an aqueous extract of H. coronarium leaves on type 2 diabetes in two types of animal models: streptozotocin (STZ)-induced T2DM in Wistar rats and C57BKSdb/db mice. Results showed improved glucose tolerance in both models. There was significant improvement of lipid profile in the STZ-induced T2DM model. Islet ß-cells lesions were decreased after extract treatment. Insulin level increased and aldosterone level decreased. Results suggest HC is a natural product worth exploring for its effect on T2DM. (39)
Antibacterial / Rhizome Oils:
Study of rhizome oil of H. coronarium yielded 46 compounds representing 98.7% of the oil identified. Main components were linalool (29.3%), limonene (20.3%), trans-meta-mentha,2,2diene (12.0%), y-terpinene (8.9%) and 10-epi-y-eudismol (3.8%). The oil showed antibacterial activity against five pathogenic bacteria viz. E. coli, S. aureus, S. typhi, P. aeruginosa, and P. vulgaris. (40)
Antiangiogenic / Cytotoxic / Diterpenoids and Diarylheptanoid / Rhizomes: Study of rhizomes isolated two new labdane diterpenoids, hedycoronals A and B (1 and 2), along with eight known diterpenoids (4-11), and a known diarylheptanoid (3). Most of the metabolites showed moderate or potent cytotoxic activities against four cancer cell lines. Compounds 3 and 8 exhibited promising inhibitory activities against HUMECs (human umbilical vein endothelial cells) with IC50s of 6.4 to 3.3 µM. (41)

Silver Nanoparticles / Synergism with Copepods Against Zika and Dengue Vector Ae. aegypti:
Study assessed the toxicity of H. coronarium rhizome extract and H. coronarium-synthesized AgNPs against larvae and pupae of the dengue vector, Aedes aegypti, as well as against adults of non-target copepod Mesocyclops formosanus. Control of A. aegypti larval population was attempted using the predatory copepod M. formosanus in synergy with H. coronarium-synthesized AgNPs. In the presence of both copepods and nano-larvicides high control of larval population was obtained. Study highlighted the potential of synergizing copepod-based control programs with highly effective green-nano larvicides in the fight against dengue and Zika virus vectors. (42)
Monoterpene Synthases Involved in Floral Scent: Flowers emit a fresh and inviting scent attributed to monoterpenes present in the profile of floral volatiles. Study yielded two novel terpene synthase (TPS) genes viz. HcTPS7 and HcTPS8, and used to study the biosynthesis of monoterpenes in H. coronarium. Results showed the HcTPS7 and HcTPS8 genes were highly expressed in petals and sepals, and expression levels in petals were positively correlated with the emission patterns of sabinene and linalool, respectively, during flower development. (43)
Antitubercular / New Labdane-Type Diterpenes / Rhizome: Study isolated two new labdane-type diterpenes, hedychicoronarin A (1) and hedychicoronarin B (2), and ten known compounds (3-12) from the rhizome of H. coronarium. Compounds (+)-coronarin A (3) and coronarin D methyl ester (4) exhibited antitubercular activities with MICs of 80 and 50 µg/mL, respectively, against Mycobacterium tuberculosis H37Rv in vitro. (44)
Silver Nanoparticles / Antibacterial / Rhizome: Study reports on the green synthesis of silver nanoparticles using rhizome extract of H. coronarium as capping, reducing, and stabilizing agent. The AgNPs showed high antibacterial activity against gram negative organisms. The antibacterial property of the silver nanoparticles has potential beneficial application in the field of medical nanotechnology. (45)


Availability

- Cultivated and wildcrafted.

Updated February 2021 /February 2016

 PHOTOS / ILLUSTRATIONS
Photos © Godofredo Stuart / StuartXchange
OTHER IMAGE SOURCE: Seeds / Hedychium coronarium J. Koenig - white garland-lily / Steve Hurst @ USDA-NRCS PLANTS Database / USDA

Additional Sources and Suggested Readings
(1)
Antimicrobial activity and chemical composition of essential oil from Hedychium coronarium / Beena Joy, Akhila Rajan, Emilia Abraham / Phytotherapy Research, May 2007; 21(5): pp 439-443 /
DOI: https://doi.org/10.1002/ptr.2091
(2)
ANTI-INFLAMMATORY AND ANALGESIC EFFECTS OF HEDYCHIUM CORONARIUM KOEN / SANGEETA SHROTRIYA, MOHAMMAD S ALI*, ACHINTO SAHA*, SITESH C BACHAR** AND MD. S ISLAM / Pak. J. Pharm. Sci., 2007, Vol.20(1), 42-47
(3)
Antioxidant and Antimicrobial Activity of Zingiberaceae Plants in Taiwan / 10.1007/s11130-007-0063-7 / Plant Foods for Human Nutrition
(4)
Antibacterial and Cytotoxic Activities of Hedychium coronarium J. Koenig / M Abdul Aziz et al / Research Journal of Agriculture and Biological Sciences, 2009; 5(6): pp 969-972

(5)
Anti-inflammation activity and chemical composition of flower essential oil from Hedychium coronarium / Y Lu, C X Zhong et al / African Journal of Biotechnology, 19 October, 2009; 8(20): pp 5373-5377 / eISSN: 1684-5315
(6)
Antioxidant and tyrosinase inhibition properties of leaves and rhizomes of ginger species / E W C Chan et al / Food Chemistry 109 (2008) 477–483
(7)
(+)-14β-Hydroxylabda-8(17),12-dieno-16,15-lactone [(+)-Isocoronarin-D]: a New Diterpene From Hedychium coronarium (Zingiberaceae) / S Singh, Al Gray, BW Skelton et al / Australian Journal of Chemistry 44 (12) 1789 - 1793 / doi:10.1071/CH9911789
(8)
Two new cytotoxic labdane diterpenes from the rhizomes of Hedychium coronarium.
/ Bioorganic & medicinal chemistry letters / ISSN: 1464-3405,
(9)
Epimers of labdane diterpenes from the rhizomes of Hedychium coronarium J. Koenig
/ F.N. Taveira; A.B. Oliveira; J.D. Souza Filho; F.C. Braga / Rev. bras. farmacogn. vol.15 no.1 João Pessoa Jan./Mar. / 2005http://dx.doi.org/10.1590/S0102-695X2005000100012
(10)
Chemical constituents of the rhizomes of Hedychium coronarium and their inhibitory effect on the pro-inflammatory cytokines production LPS-stimulated in bone marrow-derived dendritic cells. / Kiem PV, Thuy NT, Anh Hle T, Nhiem NX, Minh CV, Yen PH, Ban NK, Hang DT, Tai BH, Tuyen NV, Mathema VB, Koh YS, Kim YH. / Bioorg Med Chem Lett. 2011 Dec 15; 21(24): pp 7460-7465 / DOI: https://doi.org/10.1016/j.bmcl.2011.09.129
(11)
Sorting Hedychium names / Maintained by: Michel H. Porcher / MULTILINGUAL MULTISCRIPT PLANT NAME DATABASE / A Work in Progress / Copyright © 1997 - 2000 The University of Melbourne.
(12)
Hedychium coronarium / Common names / GLOBinMED
(13)
Chemical Composition and Trypanocidal Activity of the Essential Oils from Hedychium coronarium J. Koenig (Zingiberaceae) / Danilo Fernando Rodrigues, Angela María Arenas Velásquez, Carlos Cavaleiro, Lígia Salgueiro, Gilmárcio Zimmermann Martins, Nathália Oliveira Magalhães, Maria Bernadete Gonçalves Martins, Regina Maria Barretto Cicarelli, and Raquel Regina Duarte Moreira / ISRN Infectious Diseases, Volume 2013 (2013) / http://dx.doi.org/10.5402/2013/639275
(14)
PHYTOCHEMICAL AND PHARMACOLOGICAL EVALUATION OF HEDYCHIUM CORONARIUM J. KOENING FOR ANTIUROLITHIATIC ACTIVITY / Yogendr M. Bahuguna and Neeraj Kumar / World Journal of Pharmaceutical Sciences, 2014; 2(1): pp 112-122 / pISSN: 2321-3310 eISSN: 2321-3086
(15)
/ Phytochemical Analysis And Determination Of Total Phenolics Content In Water Extracts Of Three Species Of Hedychium / Kh. Lemino Singh1 and G.C. Bag* / International Journal of PharmTech Researchm Vol.5, No.4, pp 1516-1521, Oct-Dec 2013
(16)
Preliminary assessment of Hedychium coronarium essential oil on fibrinogenolytic and coagulant activity induced by Bothrops and Lachesis snake venoms / Cíntia A SF Miranda, Maria G Cardoso*, Mariana E Mansanares, Marcos S Gomes and Silvana Marcussi / Journal of Venomous Animals and Toxins including Tropical Diseases 2014, 20:39 doi:10.1186/1678-9199-20-39
(17)
Mosquitocidal activity of Hedychium coronarium rhizome extract and Copepod Megacyclops formosanus for the control of dengue vector Aedes aegypti / Kandasamy Kalimuthu, Jiang-Shiou Hwang*, Kadarkarai Murugan, Li-Chun Tseng / Institute of Marine Biology, National Taiwan Ocean University, Keelung 20224, Taiwan.
(18)
Antimicrobial, Mosquito Larvicidal and Antioxidant Properties of the Leaf and Rhizome of Hedychium coronarium / Jiau-Ching Ho* / Journal of the Chinese Chemical Society, Volume 58, Issue 4, pages 563–567, August 2011 / DOI: 10.1002/jccs.201190021
(19)
The Feasibility of hedychium coronarium as a paper marker ink / Lumata, Lloyd L. / DOST
(20)
Hedychium coronarium / Synonyms / The Plant List
(21)
Hypoglycemic effect of ethanolic extract of Hedychium coronarium linn., rhizome in alloxan induced diabetes in rat model. / Pranitha K, Shalini K, Pratibha M, Suneha S. / IJRPP, July-Sept 2014; 3(3)
(22)
Preliminary studies on phytochemicals and cytotoxic activity of methanolic rhizome extract of Hedychium coronarium / Pritesh Ranjan Dash, Zara Sheikh / Journal of Pharmacognosy and Phytochemistry 2015; 4(1): pp 136-139 / pISSN: 2349-8234 eISSN: 2278-4136
(23)
Floral Scent Composition in Hedychium coronarium J. Koenig Analyzed by SPME
/ JOURNAL OF ESSENTIAL OIL RESEARCH 23(3):64-67, May 2011 / DOI: 10.1080/10412905.2011.9700460
(24)
Quantification of Thiamethoxam in Rhizomes and Leaves of the Hedychium coronarium and Water and Soil by High-Pressure Liquid Chromatography / Claudine Gonçalves da Rocha, Francis Henrique Ramos França,
Claudia Andrea Lima Cardoso* / American Journal of Analytical Chemistry, 2012, 3, 242-249 / http://dx.doi.org/10.4236/ajac.2012.33032
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Antinociceptive activity of methanolic extract of the rhizomes of Hedychium coronarium
/ Poonam Singh and Surendra Raman / Asian Journal of Science and Technology
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Current status of engendared medicinal plant Hedychium coronarium and causes of populatiion decline in the natural forests of Anuppur and districts of Madhya Pradesh, India / Mishra Manish / International Research Journal of Biplogical Sceiicnes, March 2013; 2(3): pp 1-6 / ISSN: 2278-3202
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Medicinal Flowers: XXIV: Chemical Structures and Hepatoprotective Effects of Constituents from Flowers oof Hedychhium coronarium / Seikou Nakamura,, Yoshie Okazaki, Kiyofumi Ninomiya, Toshio Morilawa. Hisashi Matsuda, Masayuki Yoshikawa / Chemical and Pharmaceutical Bulletin, 2008, 56(12) : pp 1704-1709 / DOI: https:// dpo.org/10.1248/cpb.56.1704
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Evaluation of analgesic and neuropharmacological activities of methanolic rhizome extract of Hedychium coronarium / Pritesh Ranjan Dash, Mahmuda Nasrin and Moni Rani Saha / International Journal of Pharmaceutical Sciences and Research, 2011; 2(4): pp 979-984 / ISSN: 0975-8232
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Labdane-type Diiterpenes with Inhibitory Effects on Increase in Vascular Permeability and Nitric Oxide Production from Hedychium coronarium / Hisashi Matsuda, Toshio Morikawa, Yasuko Sakamoto, Iwao Toguchida, Masayuki Yoshikawa / Chemistry, August 2002; 10(8): pp 2527-2534 /
DOI: https://doii.org/10.1016/S0968-0896(02)00121-9
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Acute antihypertensive effect in conscious rats produced by some medicinal plants used in the state of São Paulo / Rosana de A Ribeiro, M Margarida R Fiuza de Melo, Fabio de Barros, Cecilia Gomes, Gustaf Trolin / Journal of Ethnopharmacology, March 1986; 15(3): pp 261-269 / DOI: https://doi.org/10.1016/0378-8741(86)90164-9
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Medicinal plants from the Yanesha (eru): Evaluation of the leishmanicidal and antimalarial activity of selected extracts / Valadeau Celine, Pabon Adriana, Deharo Eric, Castillo Denis, Bpourday Genevieve et al / Journal of Ethnopharmacology, Junne 2009; 123(3): pp 413-422 /
DOI: https://doi.org/10.1016/j.jep.2009.03.041
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Hedychium coronarium Rhizomes: Promising Antidiabetic and Natural Inhibitor of α-Amylase and α-Glucosidase / Suchitra K Panigrahy, M Tech; Awanish Kumar, PhD; and Renu Bhatt, PhD / Journal of Dietary Supplements, 2020; 17(1) / DOI: https://doi.org/10.1080/19390211.2018.1483462
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Acute diuretic effects in conscious rats produced by some medicinal plants used iin the state of Sao Paulo, Brasil / Rosana de A Ribeiro, Fabio de Barros, Celi Muniz, Silvia Chieia, Gusraf Trolin et al / Journal of Ethnopharmacology, Sept 1988 24(1): pp 19-29 / DOI: httpps://doi.org/10.1016/0378-8741(88)90136-5
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Cytotoxic Diterpenes from the Rhizomes of Hedychium coronarium / Hideji Itokawa, Hiroshi Morita, Ikuko Katou, Koichi Takeya, Mario Motidome et al / Planta Med, 1988; 54(4): pp 311-315 / DOI: 10.1055/s-3006-962442
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Composition of essential oils of four Hedychium species from Vietnam / Buii Van Thanh, Do N Dai, Tran D Thang, Nguyen Q Binh, Luu D Ngoc Anh and Isiaka A Ogunwande /
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Hedychium coronarium extract arrests cell cycle progression, induced apoptosis and impairs migration and invasion in HeLa cervical cancer cells / Asit Ray, Sudipta Gena, Nammita Mahapatra et al / Cancer Manag Res., 20019; 11: pp 483-500 / DOI" 10.2147/CMAR.S980004 / MID: 30655700 |
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Two new cytotoxic labdane diterpenes from the rhizomes ofm Hedychum coronarium / G Suresh, P Prabhakar Reddy, K Suresh Babu, Thokhir Basha Shaik, Shasi Vardhan Kalivendi / Medicinal Chemistry Letters, Dec 2010; 20(24):7544-7548 / DOI: https://doi.org/10.1016/j.bmcl.2010.9.024
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Cancer chemoprevention activity of labdane diterpenes from rizomes of Hedychium coronarium / Denise C Endringer, Francisca Taveira, Tamara Kondratyuk, John Pezzuto, Fernão Braga / Revista Brasileria de Farmacognosia, Jul-Aug 2014; 24(4): pp 408-412 / DOI: https://doi.org/10.1016/j.bjp.2014.08.002
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Glycemia Lowering Effect of an Aqueous Extract of Hedychium coronarium Leaves in Diabetic Rodent Models / Ling-Shan Tse, Po-Lin Liao, Chi-Hao Tsai, Yu Wen Cheng et al / Nutrients, 2019; 11(3) / DOI: https://doi.org/10.3390/nu11030629
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Chemical Composiition and Antibacterial Activity ohizome Oils from Hedychium coronarium Koenig and Hedychium spicatum Buch-Ham. / Om Prakkash, M Rajput, Mahesh Kumar, A K Pant / Journal of Essential Oil Bearing Plants, 2010; 13(2) / DOI: https://doi.org/10.1080/0972060X.2010.10643819
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Diterpenoids and a Diarylheptanoid from Hedychium coronarium with Significant Anti-Angiogenic and Cytotoxic Activities / Zha-Jun Zhan, Yan-Tao Wen, Feng-Yun Ren, Gui-Wei Rao et al / Cheistry & Biodiversity, Dec 2012 / DOI: https://doi.org/10.1002/cbdv.201100406
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Control of dengue and Ziika virus vector Aedes aegypti using the predatory copepod Megacyclops formosanus: Synergy with Hedychium coronarium-synthesized silver nanoparticles and related histological changes in targeted mosquitoes / Kandasamy Kalimuthu, Chellasamy Pannersevam, Chi Chour, Giovanni Benelli et al / Process Safety and Environmental Protection, July 2017; Vol 109; pp 82-96 /
DOI: https://doi.org/10.1016/j.psep.2017.03.027
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Characterization of two monoterpene synthases invovled in floral scent formation in Hedychium coronarium / Yuechong Yue, Rangcai Yu, and Yanping Fan / Planta, 2014; 240: pp 745-762
DOI: https://doi.org/10.1007/s00425-014-2127-x
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New labdane-type diterpenes and antitubercular constituents from Hedychiium coronarium / J J Chen, Y C Wu, J W Ding,, J F Chen / Planta Med, 2010 / DOI: https://doii.org/s-0030-1264520
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Evauation of antibacterial potential of silver nanoparticles (SNPs) produced using rhizome extract of Hedychium coronarium J. Koenig / Sinjumol Thomas, S John Britto, Silvy Matthew, Bince Mani / International Journal of Pharmacy and Pharmaceutical Sciences, 2014; 6(10) / ISSN: 0975-1491

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                                                            List of Understudied Philippine Medicinal Plants

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