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Family Aristolochiaceae
Barubo
Aristolochia philippinensis Warb.

Scientific names Common names
Aristolochia philippinensis Warb. Barubo (Neg.)
  Puso-pusoan (Tag.)
  Tambal-balanding (Zambales)
Aristolochia philippinensis Warb. is an accepted name. There are no recorded synonyms. The Plant List

Gen info
There are about 500 species in the Aristolochiaceae family. Most of the common ones are vines known as "Dutchman's pipe" referring to the unusual shape of the flowers that characterize the genus.

Aristolochia species have medicinal properties known to ancient Greek, Roman, Egyptian, and Chinese nedicine.
However, the genus is also known for the to contain the lethal toxin aristolochic acid. (see study below)

Aristolochia species are the larval food of swallowtail butterflies. It has been assumed that the North American pipevine swallow tail, Battus philenor is protected from its natural enemies by aristolochic acids sequestered from Aristolochia food plants. (4) (5)

Botany
Barubo is a low, shrubby, smooth plant, attaining a height of 1 meter or more. Leaves are oblong or oblong-elliptic, 14 to 21 centimeters long, 3.5 to 7 centimeters wide, with obtuse base and tapering pointed apex. Fruit is obovoid or oblong-obovoid, 2 to 2.5 centimeters long. The species differ from Aristolochia tagala in the shape of the leaves and in having a smaller fruit.

Distribution
- Endemic species.
- In thickets at low and medium altitudes, ascending up to 900 meters, in Cagayan, Isabela, Ilocos Norte, Ifugao, Benguet, Pangasinan, Zamales, Rizal, Quezon, Laguna, and Sorsogon Provinces in Luzon; in Palawan; Bancalan; and Negros.

Constituents
- Yields aristolochic acid. (see studies below) (1) (2)

Properties
- Roots considered stomachic and emmenagogue.
- Reported toxicity of aristolochic acid constituent. (see studies below)

Parts used
Roots.

Uses

Folkloric
- Decoction of roots used by Filipinos to relieve stomachache and promote menstruation.

Studies
Aristolochic Acid:
Analysis of South-East Asian troidine swallowtails showed high variability in the content of aristolochic acids among individuals. One plant specie, Aristolochia philippensis, a food plant source for the larvae, contained a high concentration of aristolochic acids. Whether the aristolochic acid provides a function in the chemical defense of the swallowtails is still an open question. (1) In one report, only one plant species, Aristolochia philippinensis, contained high concentration of aristolochic acids, while other species from various localities contained none or only marginal amounts. (5)
Aristolochic Acid / Nephrotoxic: The more than 100 cases of nephropathy reported from the use of Chinese snakeroot (Aristolochia fangchi) highlights the risk of using preparations containing aristolochic acid, of which the Philippine specie contains a high concentration of. This study systematically assessed the scientific literature available on the local and traditional uses of Aristolochia spp. worldwide. (2)
Aristolochic Acid / Toxicity Study: In a 1970 study, mice treated with aristolochic acid 1, the acute toxic manifestations were tachycardia, increases respiratory rate, ataxia, sedation and marked vasodilation. Short-term chronic toxic effects included hepatotoxicity, marked renal damage and mild hematologic dyscracias.
Aristolochic Acid Nephropathy: Aristolochic acid nephropathy, a progressive renal interstitial fibrosis, was reported in more than 100 patients after taking a Chinese herb, Aristolochia fangchi. Another report of a series of more than 2000 Indian patients from a population that used more than 7500 plant species raises the question that some of them could be related to Aristolochia species, including A bracteata, A tagala and A indica.

Availability
Wild-crafted.

Last Update January 2017

IMAGE SOURCE: Aristolochia philippinensis / Biology Dept. greenhouse, Florida International University, Miami, Florida, USA. / scott.zona/ Creative Commons / flickr

Additional Sources and Suggested Readings
(1)
Aristolochic acid content of South-East Asian troidine swallowtails (Lepidoptera: Papilionidae) and of Aristolochia plant species (Aristolochiaceae) / Dietrich Mebs and Michael Schneider / CHEMOECOLOGY
Volume 12, Number 1, 11-13, DOI: 10.1007/s00049-002-8321-5
(2)
Local uses of Aristolochia species and content of nephrotoxic aristolochic acid 1 and 2—A global assessment based on bibliographic sources / Michael Heinrich, Jennifer Chan et al /
Journal of Ethnopharmacology, Vol 125, Issue 1, 17 August 2009, Pages 108-144 / doi:10.1016/j.jep.2009.05.028
(3)
Aristolochia philippinensis / The Plant List
(4)
Aristolochia philippinensis / Gifford Arboretum Newsletter
(5)
Aristolochia / CNKI

It is not uncommon for links on studies/sources to change. Copying and pasting the information on the search window or using the DOI (if available) will often redirect to the new link page.

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