- Cordia is a genus of flowering plants in the borage family, Boraginaceae, comprising abut 250 species of shrubs and trees.
- The genus name Cordia honors the German botanist and pharmacist Valerius Cordus (1515-1544).
- Native range is Assam to Myanmar.
- Methanol extract of wood of Cordia fragrantissima exhibited significant activity against Leishmania major. Bioassay-guided fractionation of the extract yielded three new compounds (1-3) and five known compounds (4-8). The compounds despite the presence of asymmetric carbons, were found to be racemates. (see study below) (4)
- Wood yielded hydroquinones alliodorin, cordiachrome A, B, and C, cordiaquinol C, I, J, and K. (3)
- Study has suggested anti-leshmanial property.
Wood, bark, leaves.
- Fruit is edible, raw or cooked.
- No reported folkloric medicinal use in the Philippines.
In Myanmar, bark used to treat fever, diarrhea and skin diseases, and as antihelmintic. Fruit used as diuretic, expectorant, anthelmintic, and to treat lung and splenic diseases. (3)
- In India, the tribals of Meghalaya, northeast India, use the bark for the treatment of diarrhea and dysentery. (5)
- the Ralte communities of north eastern Mizoram north east India, apply the juice from crushed leaves to areas of melasma (common disorder of skin pigmentation). (6)
• Antileishmanial / Wood: A methanol extract of wood of Cordia fragrantissima exhibited significant activity against Leishmania major. Bioassay-guided fractionation of the extract yielded three new compounds (1-3) and five known compounds (4-8). The isolates were evaluated against the promastigote forms of Leishmania major, L. panamensis, and L. guyanensis. (4)